{"product_id":"cleveland-clinic-mellen-center-update-in-multiple-sclerosis-2025","title":"Cleveland Clinic Mellen Center Update in Multiple Sclerosis 2025","description":"\u003cdiv class=\"prod-filesize\"\u003e\n\u003cdiv class=\"prod-edition\"\u003e\n\u003cdiv class=\"pnllearningActivityInformationClass\" id=\"MainContent_MainContent_ucLearningActivityCatalog_Details___learningActivityCatalog_TopAndSectionDetails_ucLearningActivityInformation_TopAndSectionDetails_rptLearningActivityInformation_pnllearningActivityInformation_0\"\u003e\n\u003cdiv class=\"pnlLearningActivityInformationDescriptionClass\" id=\"MainContent_MainContent_ucLearningActivityCatalog_Details___learningActivityCatalog_TopAndSectionDetails_ucLearningActivityInformation_TopAndSectionDetails_rptLearningActivityInformation_pnlLearningActivityInformationDescription_0\"\u003e\n\u003cdiv class=\"pnllearningActivityInformationClass\" id=\"MainContent_MainContent_ucLearningActivityCatalog_Details___learningActivityCatalog_TopAndSectionDetails_ucLearningActivityInformation_TopAndSectionDetails_rptLearningActivityInformation_pnllearningActivityInformation_0\"\u003e\n\u003cdiv class=\"pnlLearningActivityInformationDescriptionClass\" id=\"MainContent_MainContent_ucLearningActivityCatalog_Details___learningActivityCatalog_TopAndSectionDetails_ucLearningActivityInformation_TopAndSectionDetails_rptLearningActivityInformation_pnlLearningActivityInformationDescription_0\"\u003e\n\u003cdiv class=\"prod-edition\"\u003e\n\u003cdiv class=\"field field--name-field-heading field--type-heading field--label-hidden field__item\"\u003e\n\u003cdiv class=\"columns small-12 medium-12 large-12 sidebar-full\"\u003e\n\u003cdiv class=\"elementor-element elementor-element-bbb44b8 elementor-widget elementor-widget-heading\" data-element_type=\"widget\" data-id=\"bbb44b8\" data-widget_type=\"heading.default\"\u003e\n\u003cdiv class=\"bundle--paragraph_component paragraph paragraph--type--paragraph-component paragraph--view-mode--default\"\u003e\n\u003cdiv class=\"elementor-element elementor-element-371ff86 elementor-widget elementor-widget-heading\" data-element_type=\"widget\" data-id=\"371ff86\" data-widget_type=\"heading.default\"\u003e\n\u003cdiv class=\"elementor-widget-container\"\u003e\n\u003cdiv class=\"elementor-element elementor-element-371ff86 elementor-widget elementor-widget-heading\" data-element_type=\"widget\" data-id=\"371ff86\" data-widget_type=\"heading.default\"\u003e\n\u003cdiv class=\"elementor-widget-container\"\u003e\n\u003cdiv class=\"description-accordion-container\"\u003e\u003csection aria-labelledby=\"book-description-heading\" class=\"font-serif description-container is-accordion\" id=\"description\"\u003e\n\u003cdiv class=\"description-content\"\u003e\n\u003cdiv\u003e\n\u003cdiv\u003e\n\u003cdiv class=\"prod-edition\"\u003e\n\u003ch3\u003eCleveland Clinic Mellen Center Update in Multiple Sclerosis 2025\u003c\/h3\u003e\n\u003cstrong\u003eInclude: 15 videos + 15 audios + 15 file sub vtt + 1 pdf, size: 6.21 GB\u003c\/strong\u003e\n\u003cbr\u003e\u003cstrong\u003eTarget Audience: m\u003cb data-index-in-node=\"0\" data-path-to-node=\"10,0,0\"\u003eeurologists, psychologists\u003c\/b\u003e\u003c\/strong\u003e\n\u003cbr\u003e\u003cstrong\u003eInformation:\u003c\/strong\u003e\n\u003cbr\u003e\u003cp data-path-to-node=\"2\"\u003e\u003cspan class=\"citation-0 recitation\"\u003eThe \u003c\/span\u003e\u003cb data-index-in-node=\"4\" data-path-to-node=\"2\"\u003e\u003cspan class=\"citation-0 recitation\"\u003eMellen Center Update in Multiple Sclerosis (MS)\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-0 recitation citation-end-0\"\u003e is the annual flagship conference hosted by the Cleveland Clinic’s world-renowned Mellen Center for MS Treatment and Research.\u003c\/span\u003e \u003cspan class=\"citation-1 recitation\"\u003eThe 2025 edition was particularly significant as it focused on the \u003c\/span\u003e\u003cb data-index-in-node=\"246\" data-path-to-node=\"2\"\u003e\u003cspan class=\"citation-1 recitation\"\u003e2024 Revisions to the McDonald Criteria\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-1 recitation citation-end-1\"\u003e, which represent the first major update to MS diagnostic guidelines in nearly a decade.\u003c\/span\u003e\u003cspan class=\"button-container hide-from-message-actions ng-star-inserted\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"3\"\u003e\u003cspan class=\"citation-2 recitation citation-end-2\"\u003eHeld as a hybrid event, the course was designed to help clinicians navigate the rapidly changing landscape of MS care, moving from “active vs. non-active” disease classifications to a more nuanced understanding of “Smoldering MS” and Progression Independent of Relapse Activity (PIRA).\u003c\/span\u003e\u003cspan class=\"button-container hide-from-message-actions ng-star-inserted\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"4\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"4\"\u003e2. What You Will Learn\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp data-path-to-node=\"5\"\u003eThe curriculum focused on integrating new diagnostic standards and therapeutic targets into daily practice. Key learning outcomes included:\u003c\/p\u003e\n\u003cul data-path-to-node=\"6\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"6,0,0\"\u003eThe New Diagnostic Standard:\u003c\/b\u003e A detailed breakdown of the \u003cb data-index-in-node=\"57\" data-path-to-node=\"6,0,0\"\u003e2024 McDonald Criteria\u003c\/b\u003e, specifically how the integration of optic nerve involvement and radiologically isolated syndrome (RIS) changes early diagnosis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"6,1,0\"\u003e“Smoldering” MS:\u003c\/b\u003e Understanding PIRA (Progression Independent of Relapse Activity) and how to identify patients who are getting worse despite having no new MRI lesions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"6,2,0\"\u003eEmerging Therapies:\u003c\/b\u003e The latest data on \u003cb data-index-in-node=\"39\" data-path-to-node=\"6,2,0\"\u003eBTK Inhibitors\u003c\/b\u003e (Bruton’s Tyrosine Kinase) and their potential to treat progressive forms of the disease by targeting microglia.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,3,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"6,3,0\"\u003eBiomarkers:\u003c\/b\u003e The clinical utility of Serum Neurofilament Light Chain (sNfL) and the “Central Vein Sign” on MRI to differentiate MS from mimics.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,4,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"6,4,0\"\u003eRehabilitation:\u003c\/b\u003e Evidence-based protocols for high-intensity aerobic exercise and intermittent fasting as neuroprotective strategies.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"7\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"7\"\u003e3. Event Details\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"8\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,0,0\"\u003e\u003cspan class=\"citation-3 recitation\"\u003eEvent:\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-3 recitation citation-end-3\"\u003e Mellen Center Update in Multiple Sclerosis (MS) 2025\u003c\/span\u003e\u003cspan class=\"button-container hide-from-message-actions ng-star-inserted\"\u003e  \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"container ng-tns-c2266573078-69 hide\"\u003e\n\u003cdiv class=\"carousel-container ng-tns-c2266573078-69\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,1,0\"\u003eDate:\u003c\/b\u003e\u003cspan class=\"citation-4 recitation citation-end-4\"\u003e June 20, 2025 (Friday)\u003c\/span\u003e\u003cspan class=\"button-container hide-from-message-actions ng-star-inserted\"\u003e  \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"container ng-tns-c2266573078-70 hide\"\u003e\n\u003cdiv class=\"carousel-container ng-tns-c2266573078-70\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,2,0\"\u003e\u003cspan class=\"citation-5 recitation\"\u003eLocation:\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-5 recitation citation-end-5\"\u003e InterContinental Hotel and Conference Center, Cleveland, Ohio, USA.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"container ng-tns-c2266573078-71 hide\"\u003e\n\u003cdiv class=\"carousel-container ng-tns-c2266573078-71\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,3,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,3,0\"\u003eFormat:\u003c\/b\u003e Hybrid (In-Person \u0026amp; Virtual Livestream).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"8,4,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"8,4,0\"\u003eHost:\u003c\/b\u003e Cleveland Clinic Mellen Center.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"9\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"9\"\u003e4. Who Should Attend\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"10\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"10,0,0\"\u003eNeurologists:\u003c\/b\u003e Specifically those treating general neurology patients who need to stay current with the new diagnostic criteria.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"10,1,0\"\u003eAdvanced Practice Providers (NPs\/PAs):\u003c\/b\u003e Who manage the long-term symptom burden of MS patients.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"10,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"10,2,0\"\u003e\u003cspan class=\"citation-6 recitation\"\u003eRehabilitation Specialists (PT\/OT):\u003c\/span\u003e\u003c\/b\u003e\u003cspan class=\"citation-6 recitation citation-end-6\"\u003e Interested in the specific “Neurorestoration” track.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"container ng-tns-c2266573078-72 hide\"\u003e\n\u003cdiv class=\"carousel-container ng-tns-c2266573078-72\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cb data-index-in-node=\"0\" data-path-to-node=\"10,3,0\"\u003ePsychologists:\u003c\/b\u003e Who manage the high prevalence of cognitive impairment and depression in this population.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"11\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"11\"\u003e5. Why Attend\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"12\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,0,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"12,0,0\"\u003eMcDonald Criteria Authors:\u003c\/b\u003e The Mellen Center faculty (including Dr. Daniel Ontaneda and Dr. Jeffrey Cohen) were key contributors to the international committee that revised the diagnostic criteria, offering attendees “primary source” explanations of the changes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,1,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"12,1,0\"\u003eComprehensive Care Model:\u003c\/b\u003e Unlike purely pharmacological conferences, this course dedicates significant time to “Wellness” topics, including diet, exercise, and sleep, which are now considered standard disease-modifying interventions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,2,0\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"12,2,0\"\u003eInteractive Debates:\u003c\/b\u003e The program features “Controversy” sessions—debates on topics like “Induction vs. Escalation Therapy” (starting with high-efficacy drugs first vs. stepping up).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"13\"\u003e\u003cb data-index-in-node=\"0\" data-path-to-node=\"13\"\u003e6. Topics\u003c\/b\u003e\u003c\/h3\u003e\n\u003cul data-path-to-node=\"15\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"15,0,0\"\u003e01 Keynote Cognitive Worsening in MS Cognitive Relapses and PIRA – Ralph Benedict\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e02 Keynote Neurorestoration in MS Where We Stand Michelle Ploughman\u003c\/li\u003e\n\u003cli\u003e03 Updates to the McDonald Criteria The 2024 Revisions Daniel Ontaneda and Karlo Toljan\u003c\/li\u003e\n\u003cli\u003e04 Improving Access to Care in Multiple Sclerosis Marisa McGinley\u003c\/li\u003e\n\u003cli\u003e05 BTK Update What we are Learning from Phase 3 Data Robert Fox\u003c\/li\u003e\n\u003cli\u003e06 Managing Mood Disorders in MS – Amy Sullivan, Grace Tworek, Brianne Markley, Raghid Charara\u003c\/li\u003e\n\u003cli\u003e07 Emerging Treatment Paradigms for MOGAD in Adults and Children – Justin Abbatemarco and Aaron Abrams\u003c\/li\u003e\n\u003cli\u003e08 Women’s Health in Neuroimmunological Disorders Alise Carlson\u003c\/li\u003e\n\u003cli\u003e09 Practical Case Studies – Use of Imaging in the New Diagnostic Criteria – Moein Amin\u003c\/li\u003e\n\u003cli\u003e10 Applications of CAR-T in Multiple Sclerosis Jeffrey Cohen and Zarmina Javed\u003c\/li\u003e\n\u003cli\u003e11 Driving Safety in Multiple Sclerosis – How to Manage a Difficult Topic – Roundtable Discussion Rebecca Cebull, Jennifer Sedlak, and Timothy Verdouw\u003c\/li\u003e\n\u003cli\u003e12 Optic Neuritis Rehabilitation for the MS Patient Alyssa DeCarlo\u003c\/li\u003e\n\u003cli\u003e13 Approaching Dysarthria Dysphagia Challenges in MS Danielle Brown\u003c\/li\u003e\n\u003cli\u003e14 Central Dizziness Vestibular Based Rehab Support Kaitlin Sparks\u003c\/li\u003e\n\u003cli\u003e15 The Complex Clinical Picture of MS in Rehab A Case Report – Alyssa DeCarlo, Danielle Brown and Kaitlin Sparks\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003csection class=\"related products\"\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003csection class=\"related products\"\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003csection class=\"related products\"\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003csection class=\"related products\"\u003e\u003c\/section\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"meducours","offers":[{"title":"Default Title","offer_id":42954528522338,"sku":"MED-AMB05392","price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/9549\/6802\/files\/Cleveland-Clinic-Mellen-Center-Update-in-Multiple-Sclerosis-2025.jpg?v=1779378992","url":"https:\/\/meducourse.com\/products\/cleveland-clinic-mellen-center-update-in-multiple-sclerosis-2025","provider":"Meducourse","version":"1.0","type":"link"}