Original release date: January 3, 2024

USCAP Pearls, Challenges and Updates in Daily Gastrointestinal Pathology Practice 2024 Join four gastrointestinal (GI) pathologists as they discuss cases of commonly encountered, yet challenging areas in GI pathology. Participants will explore the GI tract from the diagnosis and assessment of dysplasia to inflammatory disorders, iatrogenic injury, neuroendocrine neoplasms, appendiceal pathology, mesenchymal tumors, and polyps.

• Faculty will discuss how to recognize common inflammatory conditions and their mimics, look for evidence of drug induced mucosal changes in the retrieved GI specimens, and discuss other challenging situations that may lead to diagnostic error.

Learning Objectives

Upon completion of this educational activity, learners will be able to:

• Evaluate specimens from patients with inflammatory bowel disease (IBD)
• Discuss criteria to recognize and grade dysplasia throughout the GI tract
• Recognize and generate a wider differential diagnosis for biopsies of inflammatory disorders of the GI tract, be able to resolve these differentials, and distinguish from drug induced injury
• Classify the neuroendocrine proliferations and neoplasms in the GI tract
• Diagnose neoplastic lesions of the appendix and distinguish these from their mimics
• Recognize mesenchymal tumors of the GI tract, and how to distinguish them from gastrointestinal stromal tumors (GIST) and its variants
• Describe the spectrum of GI polyps, including mixed polyps, syndromic polyps, serrated polyps, and malignant polyps